Dec 1, 2014 To test this hypothesis, we evaluated glucose transporter 1 (Glut1) expression and glucose uptake by monocyte subpopulations in 

Department of Pharmacotherapy and Translational Research: “The Role of Metabolic Syndrome and Sodium-Glucose Co-Transporter 2 

Glucose Transporter 1 If you are looking for more information regarding the glucose transporter 1 (Glut1) and Glut1 deficiencies, we hope that you will find our website an excellent source of information. Glucose transporter 1 Deficiency is a rare genetic condition that affects brain metabolism. It is caused by a mutation in the SLC2A1 gene which regulates Mechanical force upregulates glucose transporter 1 (GLUT1) expression in periodontal ligament cells (PDLCs). a, b Expression of Glut1 increased after orthodontic force application in rats.a Glucose Transporter-1(glut-1) Glucose travels across the cell membrane on a transport protein. Hereditary deficiency of GLUT-1, insulin -independent transporter, results in decreased glucose transport. Patients manifest with intractable seizures in infancy and a developmental delay. GLUT-1 transporter is expressed in which of the following cell Defects in SLC2A1 are the cause of glucose transporter type 1 deficiency syndrome (GLUT1DS) [MIM:606777]; also known as blood-brain barrier glucose transport defect.

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Enzyme-linked immunosorbent assay for Antigen Detection. Size: 96 tests. Reactivity: Homo sapiens (Human) ELISA Kit for Glucose Transporter 1 (GLUT1). Enzyme-linked immunosorbent assay for Antigen Detection.

2020年6月23日 Several glucose transporter/solute carrier 2A (GLUT/SLC2A) superfamily members, including glucose transporter 1 (GLUT1), have been shown 

1 It is expressed predominantly in the kidney where it reabsorbs approximately 90% of the filtered glucose Hypoxia-inducible factor-1 (HIF-1), glucose transporter-1 (GLUT-1), and carbon anhydrase IX (CAIX) are important molecules that allow adaptation to hypoxic environments. The aim of our study was to investigate the correlation between HIF-1 , GLUT-1, and CAIX protein level with the clinicopathological features of endometrial cancer patients.

The structure of a generic GLUT glucose transporter is made up of 4 subunits per transporter. For 1 subunit, there are 12 transmembrane domains. There are 1 large extracellular loop 1 and 1 large intracellular loop 3. Amino and carboxy terminal groups are in the cytoplasm. Different Types of Glucose Transporters GLUT and their Major Tissue Expression

It is characterized by infantile seizures, delayed development, and acquired microcephaly. Transport of d-glucose across the blood-brain barrier is mediated by a sodium-independent facilitative transport protein, Glut1 (1–4).Mutations in the GLUT1 gene leading to defective function of 2018-04-15 Jinlu Wang, Hongfei Ji, Xingjian Niu, Lei Yin, Yiran Wang, Yucui Gu, Dongbo Li, Han Zhang, Minghui Lu, Fengxia Zhang, Qingyuan Zhang, " Sodium-Dependent Glucose Transporter 1 (SGLT1) Stabled by HER2 Promotes Breast Cancer Cell Proliferation by Activation of the PI3K/Akt/mTOR Signaling Pathway in HER2+ Breast Cancer ", Disease Markers,. vol. 2020, Article ID 6103542, 12 pages, 2020.

Changes in metabolic state and oxidative stress can regulate GLUT1 expression . Glucose Transporter 1 GLUT1 was the first glucose transporter to be cloned and is undoubtedly one of the most intensively studied of all membrane transport proteins. The amino acid sequence of GLUT1 is highly conserved and 98% identity exists between the sequences of human and rat GLUT1 and 97% identity between the sequences of human and mouse, rabbit, or pig. Glucose transporter-1 (GLUT-1) mediates the transport of glucose across the cellular membrane. Its elevated levels and/or activation have been shown to be associated with malignancy. The aim of this study was to investigate GLUT-1 expression in pulmonary neuroendocrine carcinomas. 2021-03-10 · Glucose transporter-1 (GLUT1) deficiency syndrome: diagnosis and treatment in late childhood.
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This gene provides instructions for producing a protein called the glucose transporter protein type 1 (GLUT1). The GLUT1 protein is embedded in the outer membrane surrounding cells , where it transports a simple sugar called glucose into cells from the blood or from other cells for use as fuel. Glucose transporter-1 (GLUT1) deficiency syndrome: diagnosis and treatment in late childhood. Gramer G(1), Wolf NI, Vater D, Bast T, Santer R, Kamsteeg EJ, Wevers RA, Ebinger F. Author information: (1)Division of Metabolic Disorders, Department of General Paediatrics, Centre for Paediatric and Adolescent Medicine, Heidelberg, Germany.

Figure 1. Mechanism of SGLT sodium ion glucose cotransport. (Adapted from Wright) [29].
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Glucose transporter type 1 deficiency syndrome (Glut1DS) is a rare genetic metabolic disorder characterized by deficiency of a protein that is required for glucose (a simple sugar) to cross the blood-brain barrier and other tissue barriers.

Diagnostic Value of Glucose Transporter 1 (GLUT-1) Expression in Nested Variant of Urothelial Carcinoma. Turkish Journal of Pathology 2019. Objective:  Identification and functional characterization of novel xylose transporters from the Biotechnology for biofuels 9 (1), 1-15, 2016. 30, 2016. Aspergillus niger membrane-associated proteome analysis for the identification of glucose transporters.

This gene provides instructions for producing a protein called the glucose transporter protein type 1 (GLUT1). The GLUT1 protein is embedded in the outer membrane surrounding cells, where it transports a simple sugar called glucose into cells from the blood or from other cells for use as fuel.

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Its elevated levels and/or activation have been shown to be associated with malignancy. The aim of this study was to investigate GLUT-1 expression in pulmonary neuroendocrine carcinomas.